Mahajan R, Singh Nr, Singh J, Dixit A, Jain A, Gupta A
Department of Pharmacology, Adesh Institute of Medical Sciences and Research, Bathinda - 151 109, India.
J Young Pharm. 2010 Jul;2(3):301-5. doi: 10.4103/0975-1483.66797.
In the last 30 years, concepts in pharmacology have moved from Essential Medicines (EM) to P-drugs via the Rational Use of Medicines (RUM), but no structured study has evaluated the level of understanding among working clinicians about these concepts. The present study is designed to fulfill that lacuna.
A cross-sectional study was carried out in and around the teaching hospitals attached to Medical Colleges, enrolling 504 clinicians from six centers across North India to fill-up a questionnaire containing 25 questions. The results were compiled using percentages and averages.
Only one-fourth of the participants claimed that they always prescribed Essential Medicines; no one could accurately count the number of drugs / drug combinations in the Indian Essential Drug list; only 15.1% of the clinicians used to write the generic names of drugs on a prescription slip; about one-third of the clinicians were not fully aware about the adverse effects, drug interactions, and contraindications of the drugs they prescribed; about 83% of the physicians admitted to rely on information from Medical Representatives (MRs) and the interest in research activities seemed to be lost.
Results show a sorry state of affairs among clinicians, as far as the level of understanding about EM, P-drugs, and RUM is concerned, and points toward arranging more continuing medical education (CME) for clinicians regarding these concepts.
在过去30年里，药理学概念已从基本药物（EM）经由合理用药（RUM）发展到个性化药物（P - drugs），但尚无结构化研究评估在职临床医生对这些概念的理解程度。本研究旨在填补这一空白。
在医学院附属教学医院及其周边开展了一项横断面研究，招募了来自印度北部六个中心的504名临床医生，以填写一份包含25个问题的问卷。结果采用百分比和平均值进行汇总。
只有四分之一的参与者声称他们总是开具基本药物；没有人能准确说出印度基本药物清单中的药物/药物组合数量；只有15.1%的临床医生习惯在处方单上写药物通用名；约三分之一的临床医生对他们所开药物的不良反应、药物相互作用和禁忌症并不完全了解；约83%的医生承认依赖医药代表提供的信息，且对研究活动的兴趣似乎丧失了。
就临床医生对基本药物、个性化药物和合理用药的理解程度而言，结果显示情况堪忧，这表明需要为临床医生安排更多关于这些概念的继续医学教育（CME）。
