Ilic Milena, Pejcic Ljiljana, Tiodorovic Branislav, Hasani Bajram, Stankovic Sandra, Milojevic Dejan, Djordjevic Daniela, Vucic Jelena, Milosevic Zaklina, Sahiti Mitat, Ristic Goran
Department of Epidemiology, University of Kragujevac Faculty of Medicine, Serbia.
Turk J Pediatr. 2010 Jul-Aug;52(4):404-8.
Neonatal tetanus is a severe, often fatal disease caused by the toxin Clostridium tetani. Neonatal tetanus is a generalized tetanus, which occurs in a neonate between 3-28 days of life. The findings indicated that tetanus in a newborn of an unvaccinated mother occurred after the application of non-sterile clay to the umbilical cord. This case was a seven-day-old male baby with progressive difficulty in feeding, trismus, hypertonicity, opisthotonos, and heart murmur. The patient was afebrile and eupneic, and had a history of non-sterile home delivery. In the past, the area of Bujanovac, Medvedja and Presevo had been exposed to mass immigration (especially due to the war in the territory of former Yugoslavia), which caused a serious problem for general practitioners, who had to be vigilant and ensure that all patients registered in their practice were fully immunized. This case has provided a clear indication of the necessity for strategies of both vaccination and ensuring hygienic conditions throughout pregnancy and delivery to prevent neonatal tetanus.
新生儿破伤风是由破伤风梭菌毒素引起的一种严重且常致命的疾病。新生儿破伤风属于全身性破伤风，发生于出生3至28天的新生儿。研究结果表明，未接种疫苗的母亲所生新生儿的破伤风是在脐带使用未经消毒的黏土后发生的。该病例为一名7天大的男婴，出现进行性喂养困难、牙关紧闭、肌张力亢进、角弓反张和心脏杂音。患者无发热，呼吸正常，有在家中未经消毒接生的病史。过去，布亚诺瓦茨、梅德韦贾和普雷舍沃地区曾经历大规模移民（尤其是由于前南斯拉夫境内的战争），这给全科医生带来了严重问题，他们必须保持警惕，确保其诊所登记的所有患者都充分接种了疫苗。该病例清楚地表明了在整个孕期和分娩过程中实施疫苗接种和确保卫生条件以预防新生儿破伤风策略的必要性。
