MMWR Morb Mortal Wkly Rep. 1998 Nov 6;47(43):928-30.
Neonatal tetanus (NT) is a severe, often fatal disease caused by a toxin of Clostridium tetani, a ubiquitous spore-forming bacterium found in high concentrations in soil and animal excrements. NT is associated with nonsterile delivery and umbilical cord-care practices for newborns of mothers with antitoxin levels insufficient to protect the newborn by transplacental transfer of maternal antibody. In 1997, NT accounted for an estimated 277,400 deaths worldwide but is rare in the United States. During 1995-1997, of 124 tetanus cases reported in the United States, only one occurred in a neonate. This report summarizes the investigation in March 1998 of an NT case by the Missoula City-County Health Department (MCCHD) and the Montana Department of Health and Human Services (MDHHS). The findings indicated that tetanus in a newborn of an unvaccinated mother occurred after application of nonsterile clay to the umbilical cord.
新生儿破伤风（NT）是一种严重的、通常致命的疾病，由破伤风梭菌的毒素引起。破伤风梭菌是一种无处不在的产芽孢细菌，在土壤和动物粪便中含量很高。NT与母亲抗毒素水平不足以通过母体抗体经胎盘转移来保护新生儿的非无菌分娩和新生儿脐带护理做法有关。1997年，NT估计在全球造成277,400人死亡，但在美国很少见。在1995 - 1997年期间，美国报告的124例破伤风病例中，只有1例发生在新生儿身上。本报告总结了1998年3月米苏拉市县卫生部门（MCCHD）和蒙大拿州卫生与公众服务部（MDHHS）对一例NT病例的调查。调查结果表明，未接种疫苗的母亲所生新生儿的破伤风是在脐带涂抹非无菌粘土后发生的。
