Melton John Jeffrey, Redding Spencer W, Kirkpatrick William R, Reasner Charles A, Ocampo Gloria L, Venkatesh Aruna, Mealey Brian L
Spec Care Dentist. 2010 Nov-Dec;30(6):230-4. doi: 10.1111/j.1754-4505.2010.00159.x. Epub 2010 Oct 21.
The goal of this study was to determine the prevalence of Candida dubliniensis and other Candida species from saliva samples and from subgingival plaque samples at periodontally healthy and periodontally diseased sites in subjects who had type 2 diabetes and periodontitis. Saliva and subgingival samples were obtained from 30 subjects with periodontitis: 15 with poorly controlled and 15 with well-controlled type 2 diabetes. Samples were analyzed for the presence of C. dubliniensis and other Candida species. Among subjects with poorly controlled diabetes, 53% were positive for C. albicans, 20% for C. glabrata, 6% for C. tropicalis, and 6% for C. parapsilosis. Among well-controlled subjects, 33% were positive for C. albicans and 13% for C. glabrata; none had C. tropicalis or C. parapsilosis. No samples were positive for C. dubliniensis in either group of subjects.
本研究的目的是确定2型糖尿病合并牙周炎患者牙周健康部位和牙周病损部位唾液样本及龈下菌斑样本中都柏林念珠菌和其他念珠菌属的流行情况。从30名牙周炎患者中获取唾液和龈下样本：其中15名2型糖尿病控制不佳患者，15名2型糖尿病控制良好患者。分析样本中都柏林念珠菌和其他念珠菌属的存在情况。在糖尿病控制不佳的患者中，白色念珠菌阳性率为53%，光滑念珠菌为20%，热带念珠菌为6%，近平滑念珠菌为6%。在控制良好的患者中，白色念珠菌阳性率为33%，光滑念珠菌为13%；无人感染热带念珠菌或近平滑念珠菌。两组患者中均无都柏林念珠菌阳性样本。
