Department of Biomaterials, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Clin Oral Implants Res. 2011 Feb;22(2):129-34. doi: 10.1111/j.1600-0501.2010.02016.x. Epub 2010 Oct 6.
The purpose of the present study was to investigate the influence of different implant placement techniques on the early bone healing response in an animal model.
In the present study, 24 cylindrical-screw-type implants with a diameter of 4.2 mm (Dyna®) were installed, using three different surgical techniques; (1) 5% undersized, using a final drill diameter of 4 mm; (2) 15% undersized, using a final drill diameter of 3.6 mm; and (3) 25% undersized, using a final drill diameter of 3.2 mm. After 3 weeks of implantation period, the peri-implant bone response was histologically evaluated and the percentage of bone-implant contact (%BIC) calculated.
New bone formation was more pronounced for implants placed with the 5% undersized or 15% undersized technique, as compared with implants installed with the 25% undersized technique. Histomorphometrical data corroborates these findings as the %BIC was significantly higher for implants inserted with the 5% undersized (47.7 ± 11.1) or 15% undersized protocol (47.5 ± 9.5) as compared with implants inserted with the 25% undersized technique (32.1 ± 9.7). No significant difference in %BIC could be observed between the 5% undersized and 15% undersized installed implants.
Within the limitation of the present study, it was concluded that excessive compression of the host bone, when a discrepancy between implant and final drill diameter more than 15%, can result in an inferior tissue response in the early stage of healing. To compare research results in the future, it is advised to specify the term "undersized" by mentioning the real reduction in diameter.
本研究旨在探讨不同种植体植入技术对动物模型早期骨愈合反应的影响。
本研究共植入 24 枚直径为 4.2mm 的圆柱形螺钉式种植体(Dyna®),采用三种不同的手术技术:(1)5%小直径,最终钻头直径为 4mm;(2)15%小直径,最终钻头直径为 3.6mm;(3)25%小直径,最终钻头直径为 3.2mm。植入 3 周后,对种植体周围骨反应进行组织学评价,并计算骨-种植体接触率(%BIC)。
与 25%小直径植入组相比,5%小直径或 15%小直径植入组的新骨形成更为明显。组织形态计量学数据证实了这一发现,5%小直径植入组(47.7±11.1)和 15%小直径植入组(47.5±9.5)的%BIC 明显高于 25%小直径植入组(32.1±9.7)。5%小直径和 15%小直径植入组之间的%BIC 无显著差异。
在本研究的限制范围内,当种植体与最终钻头直径的差异超过 15%时,过度压缩宿主骨会导致早期愈合阶段组织反应较差。为了在未来比较研究结果,建议通过提及实际直径减小量来指定“小直径”这一术语。