运动与认知：来自全国长期护理调查的结果。
Exercise and cognition: results from the National Long Term Care Survey.
机构信息
The Institute on Aging, University of Pennsylvania, PA, USA.
出版信息
Alzheimers Dement. 2010 Nov;6(6):448-55. doi: 10.1016/j.jalz.2010.02.004.
Abstract
BACKGROUND
Age remains a robust risk factor for Alzheimer's disease as well as other dementias. Therefore, the aging of the population in the United States will result in dramatic increases in the prevalence of dementia if preventative interventions are not identified. The aim of this study was to examine potential associations between exercise and lowering the risk of cognitive impairment.
METHODS
National Long Term Care Survey data were used. Level of exercise participation was measured at baseline (1994) and cognitive impairment status was measured at baseline and 5- and 10-year follow-up. Linear regression was performed, controlling for age, sex, education, baseline score on cognitive test, diabetes, and hypertension.
RESULTS
At 10-year follow-up, the number of different types of exercises performed was inversely associated with the onset of cognitive impairment (P = .002) as was the number of exercise sessions lasting at least 20 minutes (P = .007).
CONCLUSION
Study results from National Long Term Care Survey data provide evidence supporting the potential for exercise to lower the risk of dementia.
摘要
背景
年龄仍然是阿尔茨海默病和其他痴呆症的一个强有力的风险因素。因此，如果不能确定预防措施，美国人口的老龄化将导致痴呆症的患病率显著增加。本研究的目的是探讨运动与降低认知障碍风险之间的潜在关联。
方法
使用国家长期护理调查数据。在基线（1994 年）测量运动参与水平，在基线和 5 年及 10 年随访时测量认知障碍状况。进行线性回归，控制年龄、性别、教育程度、认知测试的基线得分、糖尿病和高血压。
结果
在 10 年随访时，进行的不同类型运动的次数与认知障碍的发生呈负相关（P=0.002），持续至少 20 分钟的运动次数也与认知障碍的发生呈负相关（P=0.007）。
结论
国家长期护理调查数据的研究结果为运动降低痴呆风险的潜力提供了证据支持。
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