一种早产儿神经发育风险与保护的模型。
A model of neurodevelopmental risk and protection for preterm infants.
作者信息
Pickler Rita H, McGrath Jacqueline M, Reyna Barbara A, McCain Nancy, Lewis Mary, Cone Sharon, Wetzel Paul, Best Al
机构信息
Department of Family and Community Health Nursing, School of Nursing, VCU Health System, Richmond, Virginia 23298, USA.
出版信息
J Perinat Neonatal Nurs. 2010 Oct-Dec;24(4):356-65. doi: 10.1097/JPN.0b013e3181fb1e70.
Abstract
The purpose of this article is to introduce a model of neurodevelopmental risk and protection that may explain some of the relationships among biobehavioral risks, environmental risks, and caregiving behaviors that potentially contribute to neurobehavioral and cognitive outcomes. Infants born before 30 weeks of gestation have the poorest developmental prognosis of all infants. These infants have lengthy hospitalization periods in the neonatal intensive care unit (NICU,) an environment that is not always supportive of brain development and long-term developmental needs. The model supports the premise that interventions focused on neuroprotection during the neonatal period have the potential to positively affect long-term developmental outcomes for vulnerable very preterm infants. Finding ways to better understand the complex relationships among NICU-based interventions and long-term outcomes are important to guiding caregiving practices in the NICU.
摘要
本文的目的是介绍一种神经发育风险与保护模型，该模型或许能够解释生物行为风险、环境风险与养育行为之间的某些关系，这些关系可能会对神经行为和认知结果产生影响。妊娠30周前出生的婴儿，其发育预后是所有婴儿中最差的。这些婴儿在新生儿重症监护病房（NICU）的住院时间很长，而该环境并不总是有利于大脑发育和长期发育需求。该模型支持这样一个前提，即专注于新生儿期神经保护的干预措施有可能对脆弱的极早产儿的长期发育结果产生积极影响。找到更好地理解基于NICU的干预措施与长期结果之间复杂关系的方法，对于指导NICU的护理实践非常重要。
相似文献
1
A model of neurodevelopmental risk and protection for preterm infants.一种早产儿神经发育风险与保护的模型。
J Perinat Neonatal Nurs. 2010 Oct-Dec;24(4):356-65. doi: 10.1097/JPN.0b013e3181fb1e70.
2
A model of neurodevelopmental risk and protection for preterm infants.一种早产儿神经发育风险与保护模型。
Adv Neonatal Care. 2013 Oct;13 Suppl 5(Suppl 5):S11-20. doi: 10.1097/ANC.0000000000000022.
3
Impact of hospital-based environmental exposures on neurodevelopmental outcomes of preterm infants.基于医院的环境暴露对早产儿神经发育结局的影响。
Curr Opin Pediatr. 2015 Apr;27(2):254-60. doi: 10.1097/MOP.0000000000000190.
4
Brain-oriented care in the NICU: a case study.新生儿重症监护病房中的脑导向护理：一项案例研究。
Neonatal Netw. 2014 Sep-Oct;33(5):263-7. doi: 10.1891/0730-0832.33.5.263.
5
Environmental impact of the NICU on developmental outcomes.新生儿重症监护病房对发育结局的环境影响。
J Pediatr Nurs. 1998 Oct;13(5):279-89. doi: 10.1016/S0882-5963(98)80013-4.
6
Developmental care does not alter sleep and development of premature infants.发育关怀不会改变早产儿的睡眠和发育情况。
Pediatrics. 1997 Dec;100(6):E9. doi: 10.1542/peds.100.6.e9.
7
Developmental care for promoting development and preventing morbidity in preterm infants.促进早产儿发育和预防发病的发育照护
Cochrane Database Syst Rev. 2001(4):CD001814. doi: 10.1002/14651858.CD001814.
8
Developmental care for promoting development and preventing morbidity in preterm infants.促进早产儿发育和预防发病的发育照护
Cochrane Database Syst Rev. 2000(4):CD001814. doi: 10.1002/14651858.CD001814.
9
Developmental care for promoting development and preventing morbidity in preterm infants.促进早产儿发育和预防发病的发育照护
Cochrane Database Syst Rev. 2003(4):CD001814. doi: 10.1002/14651858.CD001814.
10
Impact of Neonatal Intensive Care Unit oral feeding on neuropsychomotor outcomes at 9 months of corrected age in Chinese low-birthweight preterm infants: A retrospective study.中国低出生体重早产儿生后 9 个月时校正年龄时的神经心理运动结局与新生儿重症监护病房经口喂养的影响：一项回顾性研究。
J Clin Nurs. 2019 Feb;28(3-4):420-429. doi: 10.1111/jocn.14537. Epub 2018 Jul 27.
引用本文的文献
1
Social orienting in prematurely born preschoolers: a case control study showing altered neural tuning towards voices, not faces.早产学龄前儿童的社会定向：一项病例对照研究表明，他们对声音而非面孔的神经调谐发生了改变。
Mol Autism. 2025 Jul 30;16(1):38. doi: 10.1186/s13229-025-00672-2.
2
Predicting neurodevelopmental outcomes from neonatal cortical microstructure: A conceptual replication study.从新生儿皮质微观结构预测神经发育结局：一项概念性重复研究。
Neuroimage Rep. 2023 Apr 14;3(2):100170. doi: 10.1016/j.ynirp.2023.100170. eCollection 2023 Jun.
3
Parents' experiences of psychotherapeutic support on the neonatal unit: A mixed methods systematic review to inform intervention development for a multicultural population.父母在新生儿病房接受心理治疗支持的经历：一项混合方法的系统评价，为多元文化人群的干预发展提供信息。
Nurs Crit Care. 2025 May;30(3):e13194. doi: 10.1111/nicc.13194. Epub 2024 Oct 28.
4
The Predictive Value of Amplitude-Integrated Electroencephalography for the Neurodevelopmental Outcomes of Preterm Newborns at 12 Months Corrected Age.振幅整合脑电图对矫正年龄12个月早产儿神经发育结局的预测价值
Children (Basel). 2024 Aug 13;11(8):979. doi: 10.3390/children11080979.
5
Differences in Motor Development between Preterm Infants and Full-Term Preschool Children.早产儿与足月儿学龄前儿童运动发育的差异。
Children (Basel). 2024 Feb 16;11(2):252. doi: 10.3390/children11020252.
6
Evaluation of a course for neonatal fellows on providing psychosocial support to NICU families.对新生儿科住院医师为新生儿重症监护病房（NICU）患儿家庭提供心理社会支持课程的评估。
PEC Innov. 2022 May 25;1:100053. doi: 10.1016/j.pecinn.2022.100053. eCollection 2022 Dec.
7
Is maternal negative affectivity related to psychosocial behavior of preterm and term-born toddlers through mother-child interaction?母亲的消极情感是否通过母婴互动与早产和足月出生幼儿的心理社会行为相关？
Front Psychol. 2022 Oct 3;13:975124. doi: 10.3389/fpsyg.2022.975124. eCollection 2022.
8
Combining Kangaroo Care and Live-Performed Music Therapy: Effects on Physiological Stability and Neurological Functioning in Extremely and Very Preterm Infants.袋鼠式护理与现场音乐疗法相结合：对超早产儿和极早产儿生理稳定性和神经功能的影响。
Int J Environ Res Public Health. 2021 Jun 18;18(12):6580. doi: 10.3390/ijerph18126580.
9
Longitudinal Changes in the Sensorimotor Pathways of Very Preterm Infants During the First Year of Life With and Without Intervention: A Pilot Study.早产儿在生命的第一年中有无干预的感觉运动通路的纵向变化：一项初步研究。
Dev Neurorehabil. 2021 Oct;24(7):448-455. doi: 10.1080/17518423.2021.1903602. Epub 2021 Jun 23.
10
Effectiveness of interventions on early neurodevelopment of preterm infants: a systematic review and meta-analysis.干预措施对早产儿早期神经发育影响的效果：系统评价和荟萃分析。
BMC Pediatr. 2021 Apr 29;21(1):210. doi: 10.1186/s12887-021-02559-6.
本文引用的文献
1
Integrated review of cytokines in maternal, cord, and newborn blood: part II-- associations with early infection and increased risk of neurologic damage in preterm infants.母血、脐血和新生儿血中细胞因子的综合分析：第二部分——与早产儿早期感染和神经损伤风险增加的关系。
Biol Res Nurs. 2010 Apr;11(4):377-86. doi: 10.1177/1099800409344619. Epub 2009 Dec 21.
2
Nurturing brain plasticity: impact of environmental enrichment.培育大脑的可塑性：环境富集的影响。
Cell Death Differ. 2010 Jul;17(7):1092-103. doi: 10.1038/cdd.2009.193. Epub 2009 Dec 18.
3
Distinct roles of TLR4 and CD14 in LPS-induced inflammatory responses of neonates.Toll样受体4（TLR4）和CD14在脂多糖诱导的新生儿炎症反应中的不同作用。
Pediatr Res. 2009 Aug;66(2):179-84. doi: 10.1203/PDR.0b013e3181a9f41b.
4
Developmental changes in circulating IL-8/CXCL8 isoforms in neonates.新生儿循环中白细胞介素-8/趋化因子配体8异构体的发育变化
Cytokine. 2009 Apr;46(1):12-6. doi: 10.1016/j.cyto.2008.12.022. Epub 2009 Feb 15.
5
Salivary cortisol and behavioral state responses of healthy newborn infants to tactile-only and multisensory interventions.健康新生儿对仅触觉和多感官干预的唾液皮质醇及行为状态反应。
J Obstet Gynecol Neonatal Nurs. 2009 Jan-Feb;38(1):22-34. doi: 10.1111/j.1552-6909.2008.00307.x.
6
Sucking behavior of preterm neonates as a predictor of developmental outcomes.早产新生儿的吸吮行为作为发育结局的预测指标
J Dev Behav Pediatr. 2009 Feb;30(1):16-22. doi: 10.1097/DBP.0b013e318196b0a8.
7
Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances.早产儿脑损伤：破坏性和发育性障碍的复杂混合体。
Lancet Neurol. 2009 Jan;8(1):110-24. doi: 10.1016/S1474-4422(08)70294-1.
8
Fetal and neonatal programming: evidence and clinical implications.胎儿及新生儿编程：证据与临床意义
Am J Perinatol. 2009 Mar;26(3):191-8. doi: 10.1055/s-0028-1103027. Epub 2008 Nov 21.
9
Cytokines and perinatal brain damage.细胞因子与围产期脑损伤。
Clin Perinatol. 2008 Dec;35(4):643-63, v. doi: 10.1016/j.clp.2008.07.011.
10
A comparison of executive function in very preterm and term infants at 8 months corrected age.8个月矫正年龄时极早产儿与足月儿执行功能的比较。
Early Hum Dev. 2009 Apr;85(4):225-30. doi: 10.1016/j.earlhumdev.2008.10.005. Epub 2008 Nov 8.
Zotero 插件