Rylander Lucas S, Milbrandt Joseph C, Armington Evan, Wilson Marty, Olysav David J
Division of Orthopaedic Surgery and Rehabilitation, Southern Illinois University School of Medicine, Springfield, IL 62794-9679, USA.
Iowa Orthop J. 2010;30:89-93.
An increase in the utilization of metallic devices for orthopaedic interventions from joint replacement to fracture fixation has raised concern over local metal ion release and possible systemic sequelae due to dissemination of these ions. Our purpose was to determine whether serum titanium concentrations were elevated in patients who had previously received a locked volar distal radius plate. Our hypothesis was that the simple presence of titanium alone in a relatively fixed implant was not enough to raise serum titanium levels. Twenty-two potential subjects who had received a volar locked distal radius plate were identified through review of a single surgeon's operative logs. Eleven met inclusion criteria. Serum titanium levels were measured in these subjects and compared to both current and historical control groups. We found no difference between controls and our study group with the exception of one control subject who is employed as a welder. This is in contrast to previous studies from our institution which found increases in titanium levels in hip and spine implants. We conclude that a locking titanium volar distal radius plate does not raise serum titanium levels in this population.
从关节置换到骨折固定，用于骨科干预的金属器械使用量的增加引发了人们对局部金属离子释放以及这些离子传播可能导致的全身后遗症的担忧。我们的目的是确定既往接受过锁定掌侧桡骨远端钢板治疗的患者血清钛浓度是否升高。我们的假设是，相对固定的植入物中仅单纯存在钛不足以提高血清钛水平。通过查阅一位外科医生的手术记录，确定了22名曾接受掌侧锁定桡骨远端钢板治疗的潜在受试者。其中11名符合纳入标准。对这些受试者的血清钛水平进行了测量，并与当前和历史对照组进行了比较。除了一名从事焊接工作的对照受试者外，我们发现对照组与研究组之间没有差异。这与我们机构之前的研究形成对比，之前的研究发现髋关节和脊柱植入物中的钛水平有所升高。我们得出结论，锁定钛掌侧桡骨远端钢板不会使该人群的血清钛水平升高。
