Bidikar Mukta P, Ichaporia Rati B
Department of Physiology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai 400 008.
Indian J Physiol Pharmacol. 2010 Jan-Mar;54(1):73-9.
Fifty Rheumatoid arthritis (RA) patients between the age group of 20 to 60 years were investigated for sympathetic autonomic functions using standard tests. All the patients liable to develop dysautonomia or having a treatment interfering with autonomic nervous system were excluded. Previous studies to evalute sympathetic nervous system involvement used only a single test like sweating response, orthostatic test. In the present study 3 tests of sympathetic nervous system evaluation have been used. The evaluation was done by cardiovascular tests like orthostatic test, sustained hand grip and cold pressor test. A control series of 50 healthy subjects was tested to determine abnormal threshold for each one of the 3 tests. The reference value of Ewing and Clark were used to interpret the results of the tests. Sympathetic dysfuction was found in 26% of rheumatoid arthritis patients.
对50名年龄在20至60岁之间的类风湿性关节炎（RA）患者进行了标准测试，以研究交感神经自主功能。所有易发生自主神经功能障碍或正在接受干扰自主神经系统治疗的患者均被排除。先前评估交感神经系统受累情况的研究仅使用了单一测试，如出汗反应、直立试验。在本研究中，使用了3种交感神经系统评估测试。评估通过心血管测试进行，如直立试验、持续握力试验和冷加压试验。对50名健康受试者的对照系列进行测试，以确定这3种测试中每种测试的异常阈值。使用尤因和克拉克的参考值来解释测试结果。在26%的类风湿性关节炎患者中发现了交感神经功能障碍。
