Rossi Ethan A, Roorda Austin
School of Optometry, University of California, Berkeley, CA 94720, USA.
J Vis. 2010 Oct 1;10(12):11. doi: 10.1167/10.12.11.
The visual benefit of correcting high-order aberrations may not be fully realized due to neural mechanisms that compensate for the aberrations of the eye. We examined the extent to which these neural mechanisms might be susceptible to perceptual learning in an adaptive optics (AO)-corrected test of visual resolution. Visual resolution was measured in an adaptive optics scanning laser ophthalmoscope (AOSLO) in 3 conditions: (1) low-order correction (defocus and astigmatism) without AO, (2) 3-mm pupil with AO correction, and (3) 5.81-mm pupil with AO correction. Measurements were made on both eyes in all three conditions before training. Subjects underwent 5 days of monocular training in both AO-corrected conditions and were retested in all three conditions in both eyes after training. The range of minimum angle of resolution (MAR) for each condition was: (1) without AO: 0.53-0.95 arcmin, (2) AO 3-mm pupil: 0.33-0.6 arcmin, and (3) AO 5.81-mm pupil: 0.36-0.56 arcmin. AO correction provided an immediate and significant improvement in visual resolution. There was no significant difference in resolution when correcting aberrations over a 5.81-mm pupil versus a 3-mm pupil. Training on this task provided a minimal improvement in performance. Adaptation to aberrations did not hinder AO correction from providing an immediate visual benefit.
由于眼睛像差的神经补偿机制，矫正高阶像差的视觉益处可能无法完全实现。我们在视觉分辨率的自适应光学（AO）校正测试中，研究了这些神经机制在多大程度上可能易受知觉学习的影响。在自适应光学扫描激光检眼镜（AOSLO）中，于3种条件下测量视觉分辨率：（1）无AO的低阶校正（散焦和散光）；（2）3毫米瞳孔且有AO校正；（3）5.81毫米瞳孔且有AO校正。在训练前，对所有三种条件下的双眼进行测量。受试者在两种AO校正条件下均接受了5天的单眼训练，训练后对双眼在所有三种条件下再次进行测试。每种条件下最小分辨角（MAR）的范围为：（1）无AO：0.53 - 0.95角分；（2）AO 3毫米瞳孔：0.33 - 0.6角分；（3）AO 5.81毫米瞳孔：0.36 - 0.56角分。AO校正使视觉分辨率立即得到显著提高。在5.81毫米瞳孔与3毫米瞳孔上校正像差时，分辨率没有显著差异。针对此任务的训练对表现的改善极小。对像差的适应并未阻碍AO校正带来即时的视觉益处。
