School of Optometry, University of California, Berkeley, Berkeley, United States.
Carl Zeiss Meditec AG, Berlin, Germany.
Elife. 2019 Jul 26;8:e47148. doi: 10.7554/eLife.47148.
We provide the first measures of foveal cone density as a function of axial length in living eyes and discuss the physical and visual implications of our findings. We used a new generation Adaptive Optics Scanning Laser Ophthalmoscope to image cones at and near the fovea in 28 eyes of 16 subjects. Cone density and other metrics were computed in units of visual angle and linear retinal units. The foveal cone mosaic in longer eyes is expanded at the fovea, but not in proportion to eye length. Despite retinal stretching (decrease in cones/mm), myopes generally have a higher angular sampling density (increase in cones/deg) in and around the fovea compared to emmetropes, offering the potential for better visual acuity. Reports of deficits in best-corrected foveal vision in myopes compared to emmetropes cannot be explained by increased spacing between photoreceptors caused by retinal stretching during myopic progression.
我们提供了活体眼中文黄斑中心凹锥体细胞密度与眼轴长度关系的初步测量结果，并讨论了我们研究结果的物理和视觉意义。我们使用新一代自适应光学扫描激光检眼镜，对 16 名受试者的 28 只眼中的黄斑区及其附近的锥体细胞进行了成像。锥体细胞密度和其他指标以视角和线性视网膜单位为单位进行计算。在较长眼的中文黄斑中心凹，锥体细胞镶嵌向中文黄斑中心凹扩展，但扩展比例与眼轴不成比例。尽管存在视网膜拉伸（中文每毫米锥体细胞数减少），但近视患者中文黄斑中心凹及其周围的角分辨率密度（中文每度锥体细胞数增加）通常高于正视眼，这为更好的视力提供了潜力。与正视眼相比，近视患者中文最佳矫正中文黄斑中心凹视力的报告不能用中文近视进展过程中视网膜拉伸导致的中文感光细胞间距增加来解释。
