Endocrinology and Metabolism Institute, F20, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Cleve Clin J Med. 2010 Nov;77(11):803-11. doi: 10.3949/ccjm.77a.10056.
Confronted with a low serum level of thyrotropin (thyroid-stimulating hormone, TSH), physicians should not jump to the conclusion that it is due to a hyperthyroid state, as other conditions and some drugs can be associated with a TSH level that is slightly low (0.1-0.4 microIU/mL) or frankly suppressed (< 0.1 microIU/mL). This review discusses how to approach a low TSH, stressing the frequent need to reassess thyroid function before making a diagnosis, the underlying processes and the drugs that can be responsible, and the degree of TSH suppression and its role in the evaluation.
面对血清促甲状腺激素（TSH）水平较低的情况，医生不应轻易下结论认为是甲亢状态，因为其他情况和一些药物也会导致 TSH 水平略低（0.1-0.4 微国际单位/毫升）或明显降低（<0.1 微国际单位/毫升）。这篇综述讨论了如何处理 TSH 降低的问题，强调在做出诊断之前经常需要重新评估甲状腺功能，讨论潜在的发生机制、可能导致 TSH 降低的药物以及 TSH 抑制的程度及其在评估中的作用。
