Hall E J, Batt R M
Department of Veterinary Pathology, University of Liverpool, UK.
J Am Vet Med Assoc. 1990 Jan 1;196(1):91-5.
Intestinal permeability in dogs with small intestinal disease was measured by quantitation of 24-hour urinary excretion of 51Cr-labeled EDTA following intragastric administration. Permeability was high in dogs with a variety of naturally acquired small intestinal diseases including wheat-sensitive enteropathy of Irish Setters, small intestinal bacterial over-growth, and giardiasis, and permeability was decreased after successful treatment. These findings indicate that the assessment of intestinal permeability may be a useful technique for detecting small intestinal disease and for monitoring the efficacy of treatment in dogs.
通过胃内给予后定量测定51Cr标记的EDTA的24小时尿排泄量，来测量患有小肠疾病的犬的肠道通透性。患有多种自然获得性小肠疾病的犬，包括爱尔兰赛特犬的小麦敏感性肠病、小肠细菌过度生长和贾第虫病，其通透性较高，成功治疗后通透性降低。这些发现表明，评估肠道通透性可能是检测犬小肠疾病和监测治疗效果的一种有用技术。
