Patrizio Pasquale, Caplan Arthur L
Yale University Fertility Center, New Haven, Connecticut 06511, USA.
Clin Obstet Gynecol. 2010 Dec;53(4):717-26. doi: 10.1097/GRF.0b013e3181f96a70.
Fertility preservation is a newly developed branch of reproductive medicine aimed at preserving the potential for genetic parenthood in adults of reproductive age or children, who are at risk of sterility before undergoing anticancer treatments. Except for embryo and semen freezing, all the available options to preserve fertility are considered experimental and thus, they raise ethical issues. In this study, we reviewed the informed consent and the risk-benefit analysis of offering experimental procedures for both adults and children when they are in vulnerable situations. In particular, children represent a special category of patients and their assent to treatment to be sought at anytime should be possible. Overall, there should be no ethical objections to offer these services as they are offered with the scope of preserving future fertility.
生育力保存是生殖医学领域新发展起来的一个分支，旨在保护处于生育年龄的成年人或儿童在接受抗癌治疗前面临不育风险时的遗传生育潜能。除胚胎和精液冷冻外，所有现有的生育力保存方法都被视为试验性的，因此引发了伦理问题。在本研究中，我们回顾了在成人和儿童处于脆弱状况时为其提供试验性程序的知情同意及风险效益分析。特别是儿童属于特殊的患者群体，应尽可能随时征求他们对治疗的同意。总体而言，提供这些服务在伦理上不应遭到反对，因为提供这些服务的目的是保存未来的生育力。
