Moffitt Cancer Center, Health Outcomes and Behavior Program, Tampa, FL 33612, USA.
Am J Bioeth. 2012;12(6):38-43. doi: 10.1080/15265161.2012.673688.
We report on the case of a 2-year-old female, the youngest person ever to undergo ovarian tissue cryopreservation (OTC). This patient was diagnosed with a rare form of sickle cell disease, which required a bone-marrow transplant, and late effects included high risk of future infertility or complete sterility. Ethical concerns are raised, as the patient's mother made the decision for OTC on the patient's behalf with the intention that this would secure the option of biological childbearing in the future. Based on Beauchamp and Childress's principlism approach of respect for autonomy, nonmaleficence, beneficence, and justice, pursing OTC was ethically justified.
我们报告了一例 2 岁女性的病例，她是接受卵巢组织冷冻保存（OTC）的年龄最小的人。该患者被诊断出患有一种罕见的镰状细胞病，需要进行骨髓移植，其晚期并发症包括未来不孕或完全不育的高风险。有人提出了伦理问题，因为患者的母亲代表患者做出了进行 OTC 的决定，目的是为未来的生育选择提供保障。基于比彻姆和邱瑞斯的自主尊重、不伤害、行善和公正的原则主义方法，追求 OTC 在伦理上是合理的。
