Barber W A, Fernando M, Chadwick D R
Department of General Surgery, Chesterfield Royal Hospital, Calow, Chesterfield S44 5BL, UK.
J Thyroid Res. 2010 Feb 7;2010:840469. doi: 10.4061/2010/840469.
Introduction. We present a case of an 89-year-old female who attended our surgical endocrine clinic with a 3-month history of a left-sided neck lump. There was no past medical history of thyroid disease. Methods. Following examination and further investigation, including core biopsy, a diagnosis of plasma cell granuloma of the thyroid was made. Biochemical testing of thyroid function and Thyroid Peroxidase Antibody was in-keeping with an associated Hashimoto's thyroiditis. Results. The patient was treated conservatively with thyroxine and regularly seen in clinic. TSH levels improved and the lump showed signs of regression. Conclusion. Plasma cell granuloma of the thyroid is rare with only 16 previously reported cases. We present a new approach to management without the use of surgery or steroids. The literature is reviewed comparing clinico-pathological features and management of other reported cases.
引言。我们报告一例89岁女性患者，她因左侧颈部肿块3个月的病史前来我们的外科内分泌门诊就诊。既往无甲状腺疾病病史。方法。经过检查及进一步检查，包括核心活检，诊断为甲状腺浆细胞性肉芽肿。甲状腺功能及甲状腺过氧化物酶抗体的生化检测结果与相关的桥本甲状腺炎相符。结果。患者接受甲状腺素保守治疗，并定期到门诊复诊。促甲状腺激素水平改善，肿块有缩小迹象。结论。甲状腺浆细胞性肉芽肿罕见，此前仅有16例报道。我们提出一种不采用手术或类固醇的新治疗方法。回顾文献，比较其他报道病例的临床病理特征及治疗方法。
