Marylilly S, Subachitra T, Ramya V
Professor, Department of Pathology, Stanley Medical College , Chennai, Tamil Nadu, India .
Assistant Professor, Department of Pathology, Stanley Medical College , Chennai, Tamil Nadu, India .
J Clin Diagn Res. 2016 Apr;10(4):ED05-7. doi: 10.7860/JCDR/2016/15159.7558. Epub 2016 Apr 1.
Inflammatory myofibroblastic tumour of thyroid is very rare. Only 18 cases reported so far. Here we report a case of Inflammatory myofibroblastic tumour with its prominent spindle cell (fibrohistiocytic) pattern in a 61-year-old male patient. The dominant histological pattern in our case was myofibroblastic in contrast to prominent lymphoplasmocytic pattern in other previously reported cases. The tumour was strongly positive for vimentin, Anaplastic lymphoma kinase and showed focal positivity for Smooth Muscle Actin. The patient was treated with total thyroidectomy and he is comfortable after surgery.
甲状腺炎性肌纤维母细胞瘤非常罕见。迄今为止仅报道了18例。在此，我们报告一例61岁男性患者的炎性肌纤维母细胞瘤，其具有显著的梭形细胞（纤维组织细胞）形态。与其他先前报道病例中显著的淋巴浆细胞形态不同，我们病例中的主要组织学形态为肌纤维母细胞性。肿瘤波形蛋白、间变性淋巴瘤激酶呈强阳性，平滑肌肌动蛋白呈局灶性阳性。该患者接受了甲状腺全切术治疗，术后情况良好。
