用于膜蛋白稳定化的串联两亲分子。
Tandem facial amphiphiles for membrane protein stabilization.
机构信息
Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.
出版信息
J Am Chem Soc. 2010 Dec 1;132(47):16750-2. doi: 10.1021/ja1072959. Epub 2010 Nov 4.
Abstract
We describe a new type of synthetic amphiphile that is intended to support biochemical characterization of intrinsic membrane proteins. Members of this new family displayed favorable behavior with four of five membrane proteins tested, and these amphiphiles formed relatively small micelles.
摘要
我们描述了一种新型的合成两亲分子，旨在支持内在膜蛋白的生化特性分析。该新家族的成员与测试的五种膜蛋白中的四种表现出良好的行为，并且这些两亲分子形成了相对较小的胶束。
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