Center to Eliminate Health Disparities, School of Health Professions, University of Texas Medical Branch, Galveston, Texas 77555, USA.
J Am Geriatr Soc. 2010 Nov;58(11):2149-53. doi: 10.1111/j.1532-5415.2010.03146.x.
To determine the effect of health-related quality of life (HRQOL) on the relationship between frailty status and survival in older Mexican-American adults.
Prospective analysis of participants in the Hispanic Established Populations for Epidemiologic Study of the Elderly.
Urban and rural areas of five southwestern states: Arizona, California, Colorado, New Mexico, and Texas.
One thousand eight Mexican-American adults aged 74 to 101 interviewed between 2005 and 2006.
Trained interviewers collected information on patient demographics, health conditions, frailty status, HRQOL, and survival.
Frailty was associated with a greater odds of death (odds ratio = 2.72, 95% confidence interval = 1.5-5.1) over a period of 2 to 3 years. After adjusting for the physical component of HRQOL, being frail (as opposed to prefrail or nonfrail) was no longer significantly associated with mortality. The mental health component of HRQOL did not affect the relationship between frailty and mortality.
Older Mexican Americans identified as frail experienced poorer survival in this sample than their prefrail or nonfrail counterparts. Adjusting for the physical component of HRQOL attenuated poorer survival in persons categorized as frail.
确定健康相关生活质量（HRQOL）对老年墨西哥裔美国人虚弱状况与生存之间关系的影响。
对西班牙裔老年人流行病学研究中的参与者进行的前瞻性分析。
五个西南部州的城市和农村地区：亚利桑那州、加利福尼亚州、科罗拉多州、新墨西哥州和德克萨斯州。
2005 年至 2006 年间接受采访的 1800 名 74 至 101 岁的墨西哥裔美国人。
经过培训的访谈者收集了患者人口统计学、健康状况、虚弱状况、HRQOL 和生存信息。
在 2 至 3 年期间，虚弱与死亡的几率更高（比值比=2.72，95%置信区间=1.5-5.1）相关。在调整了 HRQOL 的生理成分后，虚弱（相对于脆弱或非脆弱）与死亡率不再显著相关。心理健康成分的 HRQOL 并不影响虚弱与死亡率之间的关系。
在这个样本中，被认定为虚弱的老年墨西哥裔美国人比他们脆弱或非脆弱的同龄人经历了更差的生存状况。调整 HRQOL 的生理成分减轻了被归类为虚弱的人的较差的生存状况。
