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[关于肾上腺切除及激素给药后14C-烟酸在动物细胞及亚细胞结构中的渗透情况]

[On 14C-nicotinate penetration into cellular and subcellular structures of animals following adrenalectomy and hormone administration].

作者信息

Ol'shanetskaia V A, Totskii V N

出版信息

Ukr Biokhim Zh (1978). 1978 Jul-Aug;50(4):494-9.

PMID:210548
Abstract

The experiments on the Wistar line rats and mongrel dogs showed that gravitational overloading, surgical and chemical adrenalectomy, injections of certain hormones and actinomycin D affect essentially the permeability of blood cells and liver mitochondria to 14C nicotinic acid. An assumption is advanced that the transport of 14C nicotinic acid to biological structures occurs with participation of complex mechanisms, the function of which is regulated by hormones and is coupled with the processes of protein synthesis.

摘要

对Wistar系大鼠和杂种狗进行的实验表明,重力过载、手术和化学去肾上腺、注射某些激素和放线菌素D对血细胞和肝线粒体对14C烟酸的通透性有实质性影响。有人提出一种假设,即14C烟酸向生物结构的转运是通过复杂机制参与进行的,这些机制的功能受激素调节,并与蛋白质合成过程相关联。

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