Clarke P S, Ratowsky D A
Royal Hobart Hospital, Australia.
Ann Allergy. 1990 Feb;64(2 Pt 2):187-90.
A double-blind trial involving 20 asthmatic patients was carried out to test the effect of fenoterol and sodium cromoglycate alone and in combination on ventilatory function one hour after medication. The results show that fenoterol, whether alone or in combination with sodium cromoglycate, can increase the forced expiratory volume in one second (FEV1) by up to 25% both after rest and after exercise. No patient suffered a decrease in FEV1 using fenoterol, and at least 80% of them recorded an increase in ventilatory ability. Sodium cromoglycate was of no benefit in eliminating early reaction to exercise-induced asthma.
一项涉及20名哮喘患者的双盲试验开展，以测试非诺特罗和色甘酸钠单独及联合用药对用药一小时后通气功能的影响。结果显示，无论单独使用还是与色甘酸钠联合使用，非诺特罗在休息和运动后均可使一秒用力呼气量（FEV1）增加高达25%。使用非诺特罗的患者FEV1均未下降，且至少80%的患者通气能力有所提高。色甘酸钠对消除运动诱发性哮喘的早期反应无益处。
