纤毛运输：CEP290 守护着一个封闭式社区。
Ciliary trafficking: CEP290 guards a gated community.
机构信息
Department of Microbiology, Molecular Biology and Biochemistry, MMBB LSS142, University of Idaho, Moscow, ID 83844-3052, USA.
出版信息
Curr Biol. 2010 Nov 9;20(21):R928-31. doi: 10.1016/j.cub.2010.09.058.
PMID:21056833
Abstract
A recent study reveals that the large coiled-coil protein CEP290 is an integral component of the transition zone between the cell body and the cilium and functions as a gatekeeper to regulate trafficking of ciliary proteins.
摘要
最近的一项研究表明，大型卷曲螺旋蛋白 CEP290 是细胞体和纤毛之间过渡区的一个组成部分，作为调节纤毛蛋白运输的守门员发挥作用。
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