Xiao Rui, Xu X Z Shawn
Life Sciences Institute and Department of Molecular & Integrative Physiology, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, Michigan 48109, USA.
Curr Biol. 2010 Nov 9;20(21):R936-8. doi: 10.1016/j.cub.2010.09.053.
Mechanosensory transduction underlies touch, hearing and proprioception and requires mechanosensitive channels that are directly gated by forces; however, the molecular identities of these channels remain largely elusive. A new study has identified Piezo1 and Piezo2 as a novel class of mechanosensitive channels.
机械感觉转导是触觉、听觉和本体感觉的基础,需要由力直接门控的机械敏感通道;然而,这些通道的分子身份在很大程度上仍然难以捉摸。一项新研究已将Piezo1和Piezo2鉴定为一类新型的机械敏感通道。