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Development of asymptomatic pancreatitis with paradoxically high serum clozapine levels in a patient with schizophrenia and the CYP1A2*1F/1F genotype.

作者信息

Sani Gabriele, Kotzalidis Giorgio D, Simonetti Alessio, Solfanelli Andrea, Mancinelli Iginia, Calabrò Giusy, De Rossi Pietro, De Luca Ottavia, Gentile Giovanna, Lionetto Luana, Manfredi Giovanni, Girardi Nicoletta, Ambrosi Elisa, Simmaco Maurizio, Tatarelli Roberto

出版信息

J Clin Psychopharmacol. 2010 Dec;30(6):737-9. doi: 10.1097/JCP.0b013e3181faa7e3.

DOI:10.1097/JCP.0b013e3181faa7e3
PMID:21057239
Abstract
摘要

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Development of asymptomatic pancreatitis with paradoxically high serum clozapine levels in a patient with schizophrenia and the CYP1A2*1F/1F genotype.一名患有精神分裂症且具有CYP1A2*1F/1F基因型的患者出现无症状性胰腺炎，同时血清氯氮平水平反常升高。
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引用本文的文献

1
Clozapine and therapeutic drug monitoring: is there sufficient evidence for an upper threshold?氯氮平与治疗药物监测：是否有足够的证据设定上限？
Psychopharmacology (Berl). 2013 Feb;225(3):505-18. doi: 10.1007/s00213-012-2922-7. Epub 2012 Nov 22.
2
Antidopaminergic drugs and acute pancreatitis: a population-based study.抗多巴胺能药物与急性胰腺炎：一项基于人群的研究。
BMJ Open. 2012 May 11;2(3). doi: 10.1136/bmjopen-2012-000914. Print 2012.