Cancer Epidemiology Branch, National Cancer Center, Ilsandong-gu, Goyang-si, Gyeonggi-do, South Korea.
Nutr Cancer. 2010;62(8):1161-9. doi: 10.1080/01635581.2010.514660.
We evaluated the association between dietary patterns and breast cancer risk according to menopausal and hormone receptor status among Korean women. In a study with 357 cases and 357 age-matched controls, dietary patterns (vegetable-seafood and meat-starch) were derived via principle component analysis based on 39 food groups from a food frequency questionnaire. The relation between dietary patterns and breast cancer risk was assessed by using multivariate logistic regression. The vegetable-seafood pattern was inversely associated with breast cancer risk [odds ratio (OR) and 95% confidence interval (CI) for high vs. low intake = 0.14 (0.08-0.25); P for trend < 0.001]. No association between the meat-starch pattern and breast cancer risk was found. The association between dietary patterns and breast cancer risk was not modified by menopausal and combined hormone receptor status. These findings indicate that a diet rich in vegetables and seafood is associated with a decreased breast cancer risk in Korean women.
我们评估了根据绝经和激素受体状态的饮食模式与乳腺癌风险之间的关联在一项针对 357 例病例和 357 名年龄匹配对照的研究中，基于食物频率问卷中的 39 种食物，通过主成分分析得出饮食模式（蔬菜-海鲜和肉-淀粉）。通过多变量逻辑回归评估饮食模式与乳腺癌风险之间的关系。蔬菜-海鲜模式与乳腺癌风险呈负相关[高摄入量与低摄入量的比值比（OR）和 95%置信区间（CI）= 0.14（0.08-0.25）;趋势 P < 0.001]。未发现肉-淀粉模式与乳腺癌风险之间存在关联。饮食模式与乳腺癌风险之间的关联不受绝经和联合激素受体状态的影响。这些发现表明，富含蔬菜和海鲜的饮食与韩国女性患乳腺癌的风险降低有关。
