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拒绝输血的骨肉瘤患者行大手术:病例报告。

Major surgery in an osteosarcoma patient refusing blood transfusion: case report.

机构信息

Jeffrey Cheah School of Medicine and Health Sciences, Monash University Sunway Campus, Malaysia.

出版信息

World J Surg Oncol. 2010 Nov 8;8:96. doi: 10.1186/1477-7819-8-96.

DOI:10.1186/1477-7819-8-96
PMID:21059231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2991319/
Abstract

We describe an unusual case of osteosarcoma in a Jehovah's Witness patient who underwent chemotherapy and major surgery without the need for blood transfusion. This 16-year-old girl presented with osteosarcoma of the right proximal tibia requiring proximal tibia resection, followed by endoprosthesis replacement. She was successfully treated with neoadjuvant chemotherapy and surgery with the support of haematinics, granulocyte colony-stimulating factor, recombinant erythropoietin and intraoperative normovolaemic haemodilution. This case illustrates the importance of maintaining effective, open communication and exploring acceptable therapeutic alternative in the management of these patients, whilst still respecting their beliefs.

摘要

我们描述了一例 Jehovah's Witness 患者的骨肉瘤病例,该患者在未输血的情况下接受了化疗和大手术。这位 16 岁的女孩患有右侧胫骨近端骨肉瘤,需要进行胫骨近端切除术,然后进行内置物置换。她在血液制剂、粒细胞集落刺激因子、重组促红细胞生成素和术中等容血液稀释的支持下,成功地接受了新辅助化疗和手术治疗。该病例说明了在管理这些患者时,保持有效、开放的沟通并探索可接受的治疗替代方案的重要性,同时仍尊重他们的信仰。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f814/2991319/cb3d221b09d1/1477-7819-8-96-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f814/2991319/be8eeae8c1a3/1477-7819-8-96-1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f814/2991319/291a1a0d85b4/1477-7819-8-96-4.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f814/2991319/cb3d221b09d1/1477-7819-8-96-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f814/2991319/be8eeae8c1a3/1477-7819-8-96-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f814/2991319/c8dc594f0ae2/1477-7819-8-96-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f814/2991319/ff35ff6eccb9/1477-7819-8-96-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f814/2991319/291a1a0d85b4/1477-7819-8-96-4.jpg
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本文引用的文献

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2
The contemporary approach to the care of Jehovah's witnesses.耶和华见证人的当代护理方法。
J Trauma. 2008 Jul;65(1):237-47. doi: 10.1097/TA.0b013e318176cc66.
3
Jehovah's Witnesses in the emergency department: what are their rights?急诊科中的耶和华见证人:他们有哪些权利?
Emerg Med J. 2005 Dec;22(12):869-71. doi: 10.1136/emj.2004.023382.
4
Prophylactic platelet transfusion for haemorrhage after chemotherapy and stem cell transplantation.化疗和干细胞移植后出血的预防性血小板输注
Cochrane Database Syst Rev. 2004 Oct 18(4):CD004269. doi: 10.1002/14651858.CD004269.pub2.
5
Oncological management of pediatric cancer patients belonging to Jehovah's Witnesses: a two-institutional experience report.对属于耶和华见证人的小儿癌症患者的肿瘤学管理:一份双机构经验报告。
Onkologie. 2004 Apr;27(2):131-7. doi: 10.1159/000076901.
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Mortality and morbidity in patients with very low postoperative Hb levels who decline blood transfusion.拒绝输血的术后血红蛋白水平极低患者的死亡率和发病率。
Transfusion. 2002 Jul;42(7):812-8. doi: 10.1046/j.1537-2995.2002.00123.x.
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Haematological care of the Jehovah's Witness patient.耶和华见证会患者的血液学护理。
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