Department of Internal Medicine, Jeju National University Hospital, Jeju, Korea.
J Korean Med Sci. 2010 Nov;25(11):1665-8. doi: 10.3346/jkms.2010.25.11.1665. Epub 2010 Oct 26.
Nocardia farcinica is an emerging pathogen in immunocompromised hosts. Even though several species of Nocardia have been reported as causative pathogens of catheter-related blood stream infections (CRBSI), CRBSI caused by N. farcinica has not been reported. A 70-yr-old man with a tunneled central venous catheter (CVC) for home parenteral nutrition was admitted with fever for two days. Norcardia species was isolated from the blood through CVC and peripheral bloods and identified to N. farcinica by 16S rRNA and rpoB gene sequence analyses. This report emphasizes the rapid and correct identification of causative agents in infectious diseases in the selection of antimicrobial agents and the consideration of catheter removal.
星形诺卡氏菌是免疫功能低下宿主中的一种新兴病原体。尽管已有几种诺卡氏菌被报道为导管相关性血流感染 (CRBSI) 的病原体，但尚未有星形诺卡氏菌引起的 CRBSI 的报道。一名 70 岁男性因家庭肠外营养而带有隧道式中心静脉导管 (CVC)，因发热两天而入院。通过 CVC 和外周血分离出诺卡氏菌属，并通过 16S rRNA 和 rpoB 基因序列分析鉴定为星形诺卡氏菌。本报告强调在选择抗菌药物和考虑是否去除导管时，快速准确地鉴定传染病的病原体。
