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The phage therapy paradigm: prêt-à-porter or sur-mesure?

作者信息

Pirnay Jean-Paul, De Vos Daniel, Verbeken Gilbert, Merabishvili Maia, Chanishvili Nina, Vaneechoutte Mario, Zizi Martin, Laire Geert, Lavigne Rob, Huys Isabelle, Van den Mooter Guy, Buckling Angus, Debarbieux Laurent, Pouillot Flavie, Azeredo Joana, Kutter Elisabeth, Dublanchet Alain, Górski Andrzej, Adamia Revaz

机构信息

Laboratory for Molecular and Cellular Technology, Burn Wound Centre, Queen Astrid Military Hospital, 1120, Brussels, Belgium.

出版信息

Pharm Res. 2011 Apr;28(4):934-7. doi: 10.1007/s11095-010-0313-5. Epub 2010 Nov 10.

DOI:10.1007/s11095-010-0313-5
PMID:21063753
Abstract
摘要

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The phage therapy paradigm: prêt-à-porter or sur-mesure?噬菌体治疗模式:现成可用还是量身定制?
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Phage therapy in clinical practice: treatment of human infections.噬菌体疗法在临床实践中的应用:治疗人类感染。
Curr Pharm Biotechnol. 2010 Jan;11(1):69-86. doi: 10.2174/138920110790725401.
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Darwinian interventions: taming pathogens through evolutionary ecology.达尔文干预:通过进化生态学驯服病原体。
Trends Parasitol. 2010 Feb;26(2):83-92. doi: 10.1016/j.pt.2009.11.009. Epub 2009 Dec 25.
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Bacteriophage therapy for the treatment of infections.用于治疗感染的噬菌体疗法。
噬菌体疗法:发现、发展及美国食品药品监督管理局批准途径
Pharmaceuticals (Basel). 2025 Jul 26;18(8):1115. doi: 10.3390/ph18081115.
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Recent insights on challenges encountered with phage therapy against gastrointestinal-associated infections.噬菌体疗法治疗胃肠道相关感染所面临挑战的最新见解。
Gut Pathog. 2025 Aug 11;17(1):60. doi: 10.1186/s13099-025-00735-y.
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Bacteriophage Therapy in Freshwater and Saltwater Aquaculture Species.淡水和咸水养殖物种中的噬菌体疗法
Microorganisms. 2025 Apr 6;13(4):831. doi: 10.3390/microorganisms13040831.
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Bacteriophage therapy: a possible alternative therapy against antibiotic-resistant strains of .噬菌体疗法:一种对抗……抗生素耐药菌株的可能替代疗法。 (原文此处不完整,缺少具体细菌名称)
Front Microbiol. 2025 Mar 31;16:1443430. doi: 10.3389/fmicb.2025.1443430. eCollection 2025.
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Targeting Chronic Biofilm Infections With Patient-derived Phages: An In Vitro and Ex Vivo Proof-of-concept Study in Patients With Left Ventricular Assist Devices.利用患者来源的噬菌体靶向慢性生物膜感染:一项针对左心室辅助装置患者的体外和离体概念验证研究
Open Forum Infect Dis. 2025 Mar 20;12(4):ofaf158. doi: 10.1093/ofid/ofaf158. eCollection 2025 Apr.
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Thinking Phage Innovations Through Evolution and Ecology.通过进化与生态思考噬菌体创新
Phage (New Rochelle). 2024 Mar 18;5(1):5-13. doi: 10.1089/phage.2023.0047. eCollection 2024 Mar.
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Addressing the Research and Development Gaps in Modern Phage Therapy.填补现代噬菌体疗法中的研发空白。
Phage (New Rochelle). 2024 Mar 18;5(1):30-39. doi: 10.1089/phage.2023.0045. eCollection 2024 Mar.
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Bacteriophage therapy for multidrug-resistant infections: current technologies and therapeutic approaches.用于多重耐药感染的噬菌体疗法:当前技术与治疗方法
J Clin Invest. 2025 Mar 3;135(5):e187996. doi: 10.1172/JCI187996.
Curr Opin Investig Drugs. 2009 Aug;10(8):766-74.
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Quality-controlled small-scale production of a well-defined bacteriophage cocktail for use in human clinical trials.用于人体临床试验的经过质量控制的特定噬菌体混合物的小规模生产。
PLoS One. 2009;4(3):e4944. doi: 10.1371/journal.pone.0004944. Epub 2009 Mar 20.
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European regulatory conundrum of phage therapy.噬菌体疗法的欧洲监管难题
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Population and evolutionary dynamics of phage therapy.噬菌体疗法的群体与进化动力学
Nat Rev Microbiol. 2004 Feb;2(2):166-73. doi: 10.1038/nrmicro822.
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Old dogma, new tricks--21st Century phage therapy.旧教条,新把戏——21世纪的噬菌体疗法。
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The influenza vaccine licensing process.
Vaccine. 2003 May 1;21(16):1786-8. doi: 10.1016/s0264-410x(03)00073-2.
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Antagonistic coevolution between a bacterium and a bacteriophage.一种细菌与一种噬菌体之间的拮抗协同进化。
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