抗神经节苷脂 GM2 阳性吉兰-巴雷综合征与戊型肝炎感染相关。
Anti-glycolipid GM2-positive Guillain-Barre syndrome due to hepatitis E infection.
机构信息
Dublin Neurological Institute, Mater Misericordiae University Hospital, 57 Eccles Street, Dublin 7, Ireland.
出版信息
Ir J Med Sci. 2011 Mar;180(1):255-7. doi: 10.1007/s11845-010-0635-7. Epub 2010 Nov 10.
PMID:21063804
Abstract
BACKGROUND
Hepatitis E infection is most prevalent in developing countries with poor sanitation, but can also occur apparently sporadically in more developed areas.
CASE
We here report a second European case of Guillain-Barre syndrome due to hepatitis E infection in association with anti-glycolipid GM2 antibody.
INTERPRETATION
This is likely to be a specific association involving molecular mimicry, and further European cases can therefore be expected.
摘要
背景
戊型肝炎感染在卫生条件较差的发展中国家最为常见，但在卫生条件较好的发达国家也可能偶有散发。
病例报告
我们在此报告第二例欧洲病例，系戊型肝炎感染引起的格林-巴利综合征，与抗神经节苷脂 GM2 抗体相关。
阐释
这可能是一种涉及分子模拟的特定关联，因此预计还会有更多的欧洲病例。
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