Allergan Inc., 2525 Dupont Drive, Irvine, CA 92612, USA.
Curr Pain Headache Rep. 2011 Feb;15(1):70-8. doi: 10.1007/s11916-010-0157-z.
Chronic migraine is a common and disabling complication of migraine with a population prevalence of about 2%. Emerging evidence suggests that episodic migraine and chronic migraine differ not only in degree, but also in kind. Compared with patients with episodic migraine, those with chronic migraine have worse socioeconomic status, reduced health-related quality of life, increased headache-related burden (including impairment in occupational, social, and family functioning), and greater psychiatric and medical comorbidities. Each year, approximately 2.5% of patients with episodic migraine develop new-onset chronic migraine (ie, chronification). Understanding the natural disease course, improving treatment and management, and preventing the onset could reduce the enormous individual and societal burden of chronic migraine, and thus, have become important goals of headache research. This review provides a summary of the history of nomenclature and diagnostic criteria, as well as recent studies focusing on the epidemiology, natural history, and burden of chronic migraine.
慢性偏头痛是偏头痛的一种常见且使人丧失能力的并发症，其人群患病率约为 2%。新出现的证据表明，发作性偏头痛和慢性偏头痛不仅在程度上有所不同，而且在性质上也有所不同。与发作性偏头痛患者相比，慢性偏头痛患者的社会经济地位较差，健康相关生活质量降低，头痛相关负担增加（包括职业、社会和家庭功能受损），并且精神和医学合并症更多。每年，大约有 2.5%的发作性偏头痛患者新发慢性偏头痛（即慢性化）。了解自然病程、改善治疗和管理以及预防发病可以减轻慢性偏头痛给个人和社会带来的巨大负担，因此，已成为头痛研究的重要目标。本综述概述了命名和诊断标准的历史，以及最近关于慢性偏头痛的流行病学、自然病史和负担的研究。
