Karaduman Yılmaz, Muz Arzu, İren Yusuf Harun, Kıran Barış, Durmuş İsmail Eren, Takmaz Suna Akın
Ankara Training and Research Hospital, Hacettepe Neighborhood, Ulucanlar Street No:89 Altındağ, Ankara, Turkey.
Ankara Training and Research Hospital, Hacettepe District, Ulucanlar Street No:89 Altındağ, Ankara, Turkey.
Sci Rep. 2025 May 25;15(1):18217. doi: 10.1038/s41598-025-01027-w.
In our study, we aim to compare the effectiveness of unilateral and bilateral pulsed radiofrequency (PRF) treatment applied to the greater occipital nerve. Patients aged 18 and over diagnosed with chronic migraine according to the International Classification of Headache Disorders were studied. The patients received greater occipital nerve (GON) block and additional GON pulsed radiofrequency treatment under ultrasound guidance, using bilateral or unilateral local anesthetics. In patients with consistently bilateral headaches (n:22), the intervention was performed bilaterally, while in asymmetric cases (n:17), the intervention was conducted on the symptomatically dominant side. Patients' age, gender, average frequency of migraine attacks before the block, average attack duration, VAS score, and number of days analgesics were used were compared between the two groups at 1, 3, and 6 months post-application. Significant decreases in VAS scores were observed in both treatment groups, indicating that both treatments were effective. The average monthly migraine attack frequency, attack duration, and number of days of analgesic use were significantly lower within the groups compared to the pre-treatment period; however, no significant difference was found between the groups. Our study demonstrates that both treatment methods are effective in managing chronic migraine. For patients with asymmetric symptoms, intervening only on the dominant side may be sufficient.
在我们的研究中，我们旨在比较对枕大神经进行单侧和双侧脉冲射频（PRF）治疗的效果。研究对象为根据《国际头痛疾病分类》诊断为慢性偏头痛的18岁及以上患者。患者在超声引导下接受枕大神经（GON）阻滞及额外的GON脉冲射频治疗，使用双侧或单侧局部麻醉剂。对于双侧头痛持续存在的患者（n = 22），干预措施双侧进行；而对于不对称性病例（n = 17），干预措施在症状更明显的一侧进行。在治疗后1个月、3个月和6个月，比较两组患者的年龄、性别、阻滞前偏头痛发作的平均频率、平均发作持续时间、视觉模拟评分（VAS）以及使用镇痛药的天数。两个治疗组的VAS评分均显著降低，表明两种治疗方法均有效。与治疗前相比，两组内每月偏头痛发作的平均频率、发作持续时间以及使用镇痛药的天数均显著降低；然而，两组之间未发现显著差异。我们的研究表明，两种治疗方法在管理慢性偏头痛方面均有效。对于症状不对称的患者，仅对优势侧进行干预可能就足够了。
