O'Connor J S, Baldini F D, Skinner J S, Einstein M
U.S. Army Physical Fitness School, Fort Benjamin Harrison, IN 46216-5690.
Mil Med. 1990 Feb;155(2):72-5.
While the use of anabolic-androgenic steroids appears to be increasing, little is known about the long-term effects of these drugs. This study compared selected blood profiles of current and former steroid-using athletes to expected values for non-drug-using populations. The results are consistent with previous research findings that steroids can have acute negative effects on liver function, lipoprotein fractions, and testosterone production. The results suggest that side effects vary widely among individuals and are drug and dose dependent. Normal function appears to return after drug use is discontinued. These data emphasize the difficulty physicians have interpreting clinical tests when dealing with those who use or have used anabolic steroids. Clearly more research is needed regarding the effects of these drugs.
虽然合成代谢雄激素类固醇的使用似乎在增加，但对于这些药物的长期影响却知之甚少。本研究将当前和曾经使用类固醇的运动员的选定血液指标与未使用药物人群的预期值进行了比较。结果与先前的研究结果一致，即类固醇可对肝功能、脂蛋白组分和睾酮生成产生急性负面影响。结果表明，副作用在个体间差异很大，且取决于药物和剂量。停药后正常功能似乎会恢复。这些数据强调了医生在处理使用或曾经使用合成代谢类固醇的患者时，在解读临床检查结果方面存在困难。显然，关于这些药物的影响还需要更多的研究。
