Hurley B F, Seals D R, Hagberg J M, Goldberg A C, Ostrove S M, Holloszy J O, Wiest W G, Goldberg A P
JAMA. 1984 Jul 27;252(4):507-13.
To determine the relationship between lipid profiles and the type of weight training and to assess the effects of anabolic-androgenic steroids on lipids, bodybuilders and powerlifters of similar age, body fat, and testosterone levels were studied before and after androgen use. Before androgen administration powerlifters had lower levels of plasma high-density-lipoprotein cholesterol (HDL-C) and HDL2-C (38 +/- 2; 6 +/- 1 mg/dL; means +/- SE, n = 8) than bodybuilders (55 +/- 2; 12 +/- 1 mg/dL; n = 8) and runners of comparable age and body fat (47 +/- 2; 14 +/- 2 mg/dL; n = 8), while levels of low-density-lipoprotein cholesterol (LDL-C) were higher in powerlifters (138 +/- 10 mg/dL) than in bodybuilders (104 +/- 7 mg/dL) and runners (110 +/- 6 mg/dL). Therefore, powerlifters had higher LDL-C/HDL-C ratios (3.7 +/- 0.3) than bodybuilders (2.0 +/- 0.2) and runners (2.4 +/- 0.2). Androgen use by eight bodybuilders and four powerlifters lowered values of both HDL-C and HDL2-C by 55% and raised values of LDL-C (61% +/- 10%) and LDL-C/HDL-C ratios (280% +/- 40%). Therefore, the training regimen of bodybuilders is associated with a more favorable lipid profile than the training used by powerlifters. Androgen use by strength-trained athletes may increase their risk for coronary heart disease.
为了确定血脂水平与力量训练类型之间的关系，并评估合成代谢雄激素类固醇对血脂的影响，我们对年龄、体脂和睾酮水平相似的健美运动员和力量举运动员在使用雄激素前后进行了研究。在使用雄激素之前，力量举运动员的血浆高密度脂蛋白胆固醇（HDL-C）和HDL2-C水平（分别为38±2；6±1mg/dL；均值±标准误，n = 8）低于健美运动员（分别为55±2；12±1mg/dL；n = 8）以及年龄和体脂相当的跑步者（分别为47±2；14±2mg/dL；n = 8），而力量举运动员的低密度脂蛋白胆固醇（LDL-C）水平（138±10mg/dL）高于健美运动员（104±7mg/dL）和跑步者（110±6mg/dL）。因此，力量举运动员的LDL-C/HDL-C比值（3.7±0.3）高于健美运动员（2.0±0.2）和跑步者（2.4±0.2）。8名健美运动员和4名力量举运动员使用雄激素后，HDL-C和HDL2-C值降低了55%，LDL-C值升高了（61%±10%），LDL-C/HDL-C比值升高了（280%±40%）。因此，健美运动员的训练方案与比力量举运动员更有利的血脂状况相关。力量训练的运动员使用雄激素可能会增加他们患冠心病的风险。
