University of British Columbia, Paediatrics, 4480 Oak St, Vancouver, British Columbia, Canada V6H 3V4.
Disabil Rehabil. 2011;33(15-16):1330-9. doi: 10.3109/09638288.2010.531371. Epub 2010 Nov 10.
Content comparison of health-related quality of life (HRQOL) measures is currently important because of the varying use of concepts and operationalisations. Our objective was to use the International Classification of Functioning Children and Youth version (ICF-CY) as a standard by which to compare the content of all cerebral palsy (CP) disease-specific HRQOL measures.
MEDLINE and PsycINFO databases were searched up to September 2008. The content of HRQOL measures was linked to the ICF-CY by two trained assessors. Agreement was calculated using kappa (κ) statistic.
Four disease-specific HRQOL measures were identified. Three generic measures were selected as a content comparison group. A total of 576 concepts contained in the measures were identified. Eighty-nine percent (n = 510) were linked to 127 different ICF-CY categories. Overall κ agreement was 0.76 (95% CI: 0.75-0.77). Forty percent of concepts were linked to the activity and participation component. The measures varied in the number of concepts and the distribution of concepts by ICF-CY components.
The ICF-CY provided an international accepted, structured framework for the content comparison of CP-specific and generic HRQOL measures. The results will provide clinicians and researchers with additional information, useful when selecting HRQOL measures.
由于对各种概念和操作化的不同使用，目前对健康相关生活质量（HRQOL）测量的内容进行比较非常重要。我们的目的是使用国际功能、残疾和健康分类儿童及青少年版（ICF-CY）作为标准，来比较所有脑瘫（CP）疾病特异性 HRQOL 测量的内容。
检索了 MEDLINE 和 PsycINFO 数据库，截至 2008 年 9 月。两名经过培训的评估员将 HRQOL 测量的内容与 ICF-CY 联系起来。使用κ（κ）统计计算一致性。
确定了 4 种疾病特异性 HRQOL 测量方法。选择了 3 种通用测量方法作为内容比较组。共确定了 576 个存在于这些测量方法中的概念。89%（n=510）与 127 个不同的 ICF-CY 类别相关联。总体κ一致性为 0.76（95%可信区间：0.75-0.77）。40%的概念与活动和参与成分相关联。这些测量方法在概念的数量和概念在 ICF-CY 成分中的分布上存在差异。
ICF-CY 为 CP 特异性和通用 HRQOL 测量的内容比较提供了一个国际公认的、结构化的框架。结果将为临床医生和研究人员提供更多有用的信息，在选择 HRQOL 测量方法时非常有用。
