Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237 China.
Org Lett. 2010 Dec 17;12(24):5664-7. doi: 10.1021/ol102461c. Epub 2010 Nov 11.
P(n)Bu(3)-catalyzed cyclization reactions of salicylaldimines and salicylaldehydes with ethyl 2,3-butadienoate gave the corresponding functionalized chromans in moderate to good yields in THF under mild conditions. The new reaction provides a new method for the synthesis of biologically active chroman products.
P(n)Bu(3)催化水杨醛亚胺和水杨醛与乙基 2,3-丁二烯酸酯的环化反应,在温和条件下以中等至良好的产率得到相应的功能化色满。该新反应为生物活性色满产物的合成提供了一种新方法。