Department of Neonatology, Cork University Maternity Hospital, Cork, Ireland.
Acta Paediatr. 2011 Mar;100(3):360-3. doi: 10.1111/j.1651-2227.2010.02086.x. Epub 2010 Dec 3.
The current recommendation in setting up the Neopuff is to use a gas flow of 5-15 L/min. We investigated if the sensitivity of the positive end expiratory pressure (PEEP) valve varies at different flow rates within this range.
Five Neopuffs were set up to provide a PEEP of 5 cm H(2) O. The number of clockwise revolutions to complete occlusion of the PEEP valve and the mean and range of pressures at each quarter clockwise revolution were recorded at gas flow rates between 5 and 15 L/min.
At 5, 10 and 15 L/min, 0.5, 1.7 and 3.4 full clockwise rotations were required to completely occlude the PEEP valve, and pressures rose from 5 to 11.4, 18.4 and 21.5 cm H(2) O, respectively. At a flow rate of 5 L/min, half a rotation of the PEEP dial resulted in a rise in PEEP from 5 to 11.4cm H(2) O. At 10 L/min, half a rotation resulted in a rise from 5 to 7.7cm H(2) O, and at 15 L/min PEEP rose from 5 to 6.8cm H(2) O.
Users of the Neopuff should be aware that the PEEP valve is more sensitive at lower flow rates and that half a rotation of the dial at 5 L/min gas flow can more than double the PEEP.
目前推荐的 Neopuff 设置是使用 5-15 L/min 的气体流量。我们研究了在该范围内的不同流量下,呼气末正压(PEEP)阀的灵敏度是否会发生变化。
将 5 个 Neopuffs 设置为提供 5cmH2O 的 PEEP。记录在 5 至 15 L/min 的气体流量下,完成 PEEP 阀完全阻塞所需的顺时针旋转数,以及每四分之一顺时针旋转的平均压力和压力范围。
在 5、10 和 15 L/min 时,完全阻塞 PEEP 阀分别需要 0.5、1.7 和 3.4 个完整的顺时针旋转,压力分别从 5 上升到 11.4、18.4 和 21.5cmH2O。在 5 L/min 的流量下,PEEP 拨号盘旋转半圈会导致 PEEP 从 5 上升到 11.4cmH2O。在 10 L/min 时,半圈旋转会导致 PEEP 从 5 上升到 7.7cmH2O,而在 15 L/min 时,PEEP 从 5 上升到 6.8cmH2O。
Neopuff 的使用者应该意识到,PEEP 阀在较低的流量下更为敏感,并且在 5 L/min 的气体流量下,拨号盘旋转半圈可以使 PEEP 增加一倍以上。