比较灰色矿物三氧化物凝聚体与稀释甲酚醛在人类乳磨牙牙髓切断术中的应用
Comparing gray mineral trioxide aggregate and diluted formocresol in pulpotomized human primary molars.
作者信息
Zealand Cameron M, Briskie Daniel M, Botero Tatiana M, Boynton James R, Hu Jan C C
机构信息
The Center for Pediatric Dentistry, Calgary, Alberta, Canada.
出版信息
Pediatr Dent. 2010 Sep-Oct;32(5):393-9.
PURPOSE
The purpose of this multisite, multioperator, prospective, randomized, controlled clinical trial was to evaluate the 6-month outcomes of diluted formocresol (DFC) compared to gray mineral trioxide aggregate (GMTA) as pulpotomy medicament.
METHODS
Determined by a power analysis, 252 molars of 152 children were recruited. The teeth were randomly assigned to receive GMTA or DFC. At the 6-month follow-up, 118 children with 203 treated teeth were evaluated.
RESULTS
Four blinded and calibrated evaluators scored each radiograph for pathologies. Clinical success was similar for DFC (97%) and GMTA (100%), (P<.09). Radiographic success differed significantly (P<.04) for DFC (86%) and GMTA (95%). Pulp canal obliteration was radiographically observed in 25% of the DFC group and in 37% of the GMTA group (P=.07). Dentin bridging was observed in 22% of the GMTA group but was not found in the DFC group (P<.01).
CONCLUSION
Teeth treated with GMTA showed more favorable radiographic outcomes than DFC at 6 months post-treatment.
目的
本多中心、多操作者、前瞻性、随机对照临床试验的目的是评估与灰色三氧化矿物凝聚体（GMTA）相比，稀释甲酚醛（DFC）作为活髓切断术药物的6个月疗效。
方法
通过功效分析确定，招募了152名儿童的252颗磨牙。这些牙齿被随机分配接受GMTA或DFC治疗。在6个月的随访中，对118名接受治疗的203颗牙齿的儿童进行了评估。
结果
四位经过盲法校准的评估者对每张X线片的病变情况进行评分。DFC组（97%）和GMTA组（100%）的临床成功率相似（P<0.09）。DFC组（86%）和GMTA组（95%）的影像学成功率差异显著（P<0.04）。在DFC组中，25%的牙齿在影像学上观察到根管闭塞，在GMTA组中为37%（P=0.07）。在GMTA组中观察到22%的牙齿有牙本质桥形成，但在DFC组中未发现（P<0.01）。
结论
治疗后6个月，用GMTA治疗的牙齿在影像学上的疗效比DFC更理想。
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