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RNA修饰数据库(RNAMDB):2011年更新版。

The RNA Modification Database, RNAMDB: 2011 update.

作者信息

Cantara William A, Crain Pamela F, Rozenski Jef, McCloskey James A, Harris Kimberly A, Zhang Xiaonong, Vendeix Franck A P, Fabris Daniele, Agris Paul F

机构信息

The RNA Institute, University at Albany, State University of New York, 1400 Washington Avenue, Albany, NY 12222, USA.

出版信息

Nucleic Acids Res. 2011 Jan;39(Database issue):D195-201. doi: 10.1093/nar/gkq1028. Epub 2010 Nov 10.

DOI:10.1093/nar/gkq1028
PMID:21071406
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3013656/
Abstract

Since its inception in 1994, The RNA Modification Database (RNAMDB, http://rna-mdb.cas.albany.edu/RNAmods/) has served as a focal point for information pertaining to naturally occurring RNA modifications. In its current state, the database employs an easy-to-use, searchable interface for obtaining detailed data on the 109 currently known RNA modifications. Each entry provides the chemical structure, common name and symbol, elemental composition and mass, CA registry numbers and index name, phylogenetic source, type of RNA species in which it is found, and references to the first reported structure determination and synthesis. Though newly transferred in its entirety to The RNA Institute, the RNAMDB continues to grow with two notable additions, agmatidine and 8-methyladenosine, appended in the last year. The RNA Modification Database is staying up-to-date with significant improvements being prepared for inclusion within the next year and the following year. The expanded future role of The RNA Modification Database will be to serve as a primary information portal for researchers across the entire spectrum of RNA-related research.

摘要

自1994年创建以来,RNA修饰数据库(RNAMDB,http://rna-mdb.cas.albany.edu/RNAmods/)一直是有关天然存在的RNA修饰信息的汇聚点。目前,该数据库采用易于使用的可搜索界面,以获取有关当前已知的109种RNA修饰的详细数据。每个条目都提供化学结构、通用名称和符号、元素组成和质量、CA登记号和索引名称、系统发育来源、发现它的RNA种类类型,以及首次报道的结构测定和合成的参考文献。尽管RNA修饰数据库已整体新转移至RNA研究所,但该数据库仍在不断发展,去年新增了两个值得注意的条目,即胍丁胺和8-甲基腺苷。RNA修饰数据库正在紧跟步伐,为明年和后年纳入的重大改进做准备。RNA修饰数据库未来扩展后的作用将是作为涵盖整个RNA相关研究领域的研究人员的主要信息门户。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9db8/3013656/b27a8d963a9e/gkq1028f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9db8/3013656/ef7c216e748e/gkq1028f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9db8/3013656/26542c7eb761/gkq1028f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9db8/3013656/b27a8d963a9e/gkq1028f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9db8/3013656/ef7c216e748e/gkq1028f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9db8/3013656/26542c7eb761/gkq1028f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9db8/3013656/b27a8d963a9e/gkq1028f3.jpg

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