Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, Liverpool, UK.
Br J Ophthalmol. 2011 Feb;95(2):273-6. doi: 10.1136/bjo.2010.192344. Epub 2010 Nov 11.
BACKGROUND/AIMS: High viscosity silicone oils are used as tamponade agents to increase the resistance to emulsification; however, this makes the oils more difficult to inject. Increasing the extensional viscosity is one way to reduce emulsification. This study aimed to evaluate how silicone oils with increased extensional viscosity behave in terms of their ease of injection.
The shear viscosity and the length of time taken to inject 9 ml of Siluron 1000, Siluron 2000, Siluron 5000, SiliconMate, a 56/44 w/w blend of Siluron 1000/Siluron 5000 (Blend A) and a 90/10 w/w blend of Siluron 1000/PDMS 423kDa molecular weight (Blend B) were examined.
The shear viscosity of Siluron 1000, Siluron 2000 and Siluron 5000 were within the expected ranges. The shear viscosity of Blend A was 2283 mPa s, Blend B was 4710 mPa s and SiliconMate was 995.3 mPa s. Siluron 1000 and SiliconMate had the shortest injection times as expected due to their lower shear viscosities. Comparison of Siluron 2000 and Blend A demonstrated that Siluron 2000 was easier to inject. Similarly, Blend B was easier to inject than Siluron 5000.
Silicone oil blends containing small percentages of a high molecular weight additive are easier to inject than single grade oils of the equivalent shear viscosity.
背景/目的：高粘度硅油用作填塞剂以增加抗乳化性；然而，这使得油更难注入。增加拉伸粘度是减少乳化的一种方法。本研究旨在评估拉伸粘度增加的硅油在注射容易程度方面的表现。
考察了 Siluron 1000、Siluron 2000、Siluron 5000、SiliconMate、Siluron 1000/Siluron 5000（56/44 w/w 混合比，混合 A）和 Siluron 1000/PDMS 423 kDa 分子量（90/10 w/w 混合比，混合 B）的剪切粘度和注射 9 ml 所需的时间。
Siluron 1000、Siluron 2000 和 Siluron 5000 的剪切粘度均在预期范围内。混合 A 的剪切粘度为 2283 mPa s，混合 B 为 4710 mPa s，SiliconMate 为 995.3 mPa s。Siluron 1000 和 SiliconMate 由于其较低的剪切粘度，预计注射时间最短。Siluron 2000 与混合 A 的比较表明，Siluron 2000 更容易注射。同样，混合 B 比 Siluron 5000 更容易注射。
含有少量高分子量添加剂的硅油混合物比具有等效剪切粘度的单一等级油更容易注射。
