Robert Mirna, Holle Du Ry van Beest, Setiawaty V, Pangesti K N A, Sedyaningsih E R
National Institute for Public Health and the Environment (RIVM), Center for Infectious Disease Control, Bilthoven, The Netherlands.
Southeast Asian J Trop Med Public Health. 2010 Sep;41(5):1095-103.
Since 2003, about a third (> 150 cases) of human cases of highly pathogenic avian influenza (HPAI) A/H5N1 worldwide are reported from Indonesia. We measured the seroprevalence of H5N1 among Indonesian poultry farmers and assessed the risk factors for and knowledge of H5N1 infection. In 2007, poultry workers and farm residents were interviewed about risk factors for knowledge of and then examined for the seropositivity of H5N1 virus. Four hundred ninety-five of 622 farmers (80%) from 12 farms participated in the study. Of these, 71% were male, with a median age of 29 years. None tested positive for H5N1 virus. Masks were never worn by 54% of participants; 86% were afraid of becoming infected. For the preceding six months, 1 farm was confirmed as having poultry infected with H5N1 virus. No evidence of subclinical infection with avian influenza A/H5N1 virus was found among poultry farmers, although exposure of the farmers to this virus may have been limited. However, we recommend sustaining ongoing surveillance and control efforts.
自2003年以来,全球报告的高致病性禽流感(HPAI)A/H5N1人间病例中约三分之一(>150例)来自印度尼西亚。我们测量了印度尼西亚家禽养殖户中H5N1的血清阳性率,并评估了H5N1感染的危险因素及相关知识。2007年,我们对家禽工人和农场居民进行了访谈,了解他们对H5N1感染的危险因素及相关知识,然后检测他们的H5N1病毒血清阳性情况。来自12个农场的622名养殖户中有495人(80%)参与了研究。其中,71%为男性,年龄中位数为29岁。没有人H5N1病毒检测呈阳性。54%的参与者从未戴过口罩;86%的人担心会被感染。在之前的六个月里,有1个农场被确认为有家禽感染H5N1病毒。在家禽养殖户中未发现甲型H5N1禽流感病毒亚临床感染的证据,尽管养殖户接触该病毒的情况可能有限。然而,我们建议持续进行监测和防控工作。