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2006 年阿尔及利亚分离的蓝舌病病毒血清型 1 的分子流行病学。

Molecular epidemiology of bluetongue virus serotype 1 isolated in 2006 from Algeria.

机构信息

CIRAD, UMR Contrôle des Maladies, F-34398 Montpellier, France.

出版信息

Res Vet Sci. 2011 Dec;91(3):486-97. doi: 10.1016/j.rvsc.2010.10.002. Epub 2010 Nov 11.

DOI:10.1016/j.rvsc.2010.10.002
PMID:21074232
Abstract

This study reports on an outbreak of disease that occurred in central Algeria during July 2006. Sheep in the affected area presented clinical signs typical of bluetongue (BT) disease. A total of 5245 sheep in the affected region were considered to be susceptible, with 263 cases and thirty-six deaths. Bluetongue virus (BTV) serotype 1 was isolated and identified as the causative agent. Segments 2, 7 and 10 of this virus were sequenced and compared with other isolates from Morocco, Italy, Portugal and France showing that they all belong to a 'western' BTV group/topotype and collectively represent a western Mediterranean lineage of BTV-1.

摘要

本研究报告了 2006 年 7 月在阿尔及利亚中部发生的一次疾病暴发。受影响地区的绵羊呈现出典型的蓝舌病(BT)临床症状。受影响地区共有 5245 只绵羊被认为易感,发病 263 例,死亡 36 例。分离并鉴定出该病毒为蓝舌病病毒(BTV)血清型 1。该病毒的 2、7 和 10 段序列与来自摩洛哥、意大利、葡萄牙和法国的其他分离株进行了比较,结果表明它们均属于“西部”BTV 组/拓扑型,共同代表了 BTV-1 的西部地中海谱系。

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