Myara I
Laboratoire de Biochimie, Hôpital Broussais, Paris, France.
Pathol Biol (Paris). 1990 Feb;38(2):134-43.
The interest of new methodologies (electrophoresis in agarose, immunofixation, quantitation of Ig G, Ig A, Ig M and light chains kappa/lambda ratio) to diagnose monoclonal gammopathies, was discussed. A strategy using a combination of these new procedures was exposed. Serum level of bêta-2 microglobulin can be used to monitor response to therapy in myeloma when the quantitation of monoclonal Ig is not possible.
讨论了新方法（琼脂糖电泳、免疫固定、IgG、IgA、IgM定量及轻链κ/λ比值）在诊断单克隆丙种球蛋白病中的应用价值。介绍了一种联合使用这些新方法的策略。当无法对单克隆免疫球蛋白进行定量时，血清β2微球蛋白水平可用于监测骨髓瘤的治疗反应。
