D'Angelo G, Giardini C, Calvano D, Braghini T
Minerva Med. 1985 Oct 27;76(41):1921-6.
Monoclonal gammopathies have been examined and classified. In the field of chemico-clinical and immunological investigations, the various methods of analysing dysproteinaemia, of which the monoclonal component is a typical expression (electrophoresis, radial immunodiffusion, immunoelectrophoresis, immunofixation), and the main haematological and immunohaematological changes (lymphocyte biological markers) involved are reviewed. After describing the main histological and histo-cytochemical investigations, particularly amyloidosis, electronic microscope aspects and the most important chromosome abnormalities revealed by karyotype study are reported for their diagnostic interest.
单克隆丙种球蛋白病已得到研究和分类。在化学临床和免疫学研究领域，回顾了分析异常蛋白血症的各种方法（其中单克隆成分是典型表现），包括电泳、放射免疫扩散、免疫电泳、免疫固定，以及所涉及的主要血液学和免疫血液学变化（淋巴细胞生物学标志物）。在描述了主要的组织学和组织细胞化学研究，特别是淀粉样变性后，报告了电子显微镜观察结果以及核型研究揭示的最重要的染色体异常，这些内容具有诊断价值。
