Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka, 565-0871, Japan.
Chem Commun (Camb). 2011 Jan 21;47(3):1060-2. doi: 10.1039/c0cc03933k. Epub 2010 Nov 15.
A novel and rapid approach to chiral mono- or di-substituted spiroketals based on remote asymmetric induction by intramolecular iodoetherification of ene or diene ketals has been developed. This strategy concisely offers 5,5- and 5,6-spiroketals including the natural insect pheromone of the wasp.
一种新的、快速的手性单取代或双取代螺缩酮方法，基于烯或二烯缩酮的分子内碘醚化的远程不对称诱导，已经被开发出来。该策略简洁地提供了包括天然昆虫信息素的黄蜂 5,5-和 5,6-螺缩酮。
