Department of Internal Medicine, Division of Hematology, Dokuz Eylul University, Izmir, Turkey.
Clin Appl Thromb Hemost. 2011 Aug;17(4):414-20. doi: 10.1177/1076029610385672. Epub 2010 Nov 15.
Depending on type, duration, and intensity of the exercise, changes occur in hemostasis. In this study, we evaluated the changes in the parameters of coagulation and fibrinolytic systems that happened after the submaximal aerobic exercises by bicycle ergomater. Twelve healthy male participants whose ages were between 21 and 28 have been included. The venous samples have been drawn before the exercise as well as at the 0 th, 15th, and 60th minutes after the submaximal exercise. The values of prothrombin time (PT), active partial thromboplastin time (aPTT), D-dimer, fibrinogen, plasminogen activator inhibitor 1 (PAI-1) and thrombin-activatable fibrinolysis inhibitor (TAFI) have been measured. Plasminogen activator inhibitor 1 values have shown an insignificant increase after exercise (P = .328), whereas, it has decreased significantly during the resting period (P = .033) Postexercise 15th and 60th minutes TAFI values have decreased significantly comparing to basal and postexercise (0 th minute) values (P = .001). Fibrinolytic system activation is observed after acute submaximal aerobic exercise of sedentary healthy participants.
根据运动的类型、持续时间和强度，止血会发生变化。在这项研究中，我们评估了自行车测力计进行亚最大有氧运动后凝血和纤维蛋白溶解系统参数的变化。 12 名年龄在 21 至 28 岁之间的健康男性参与者被纳入研究。在运动前以及运动后 0 分钟、15 分钟和 60 分钟时抽取静脉血样。测量了凝血酶原时间（PT）、活化部分凝血活酶时间（aPTT）、D-二聚体、纤维蛋白原、纤溶酶原激活物抑制剂 1（PAI-1）和凝血酶激活的纤维蛋白溶解抑制剂（TAFI）的值。运动后纤溶酶原激活物抑制剂 1 的值没有明显增加（P =.328），而在休息期间显著下降（P =.033）。与基础值和运动后（0 分钟）值相比，运动后 15 分钟和 60 分钟的 TAFI 值显著降低（P =.001）。久坐健康参与者进行急性亚最大有氧运动后，纤维蛋白溶解系统被激活。
