大挑战述评：将生物合成转化为信息科学。

Grand challenge commentary: Transforming biosynthesis into an information science.

机构信息

Centre for Synthetic Biology and Innovation, Imperial College London, London, UK.

出版信息

Nat Chem Biol. 2010 Dec;6(12):859-61. doi: 10.1038/nchembio.487.

Abstract

Engineering biosynthetic pathways to natural products is a challenging endeavor that promises to provide new therapeutics and tools to manipulate biology. Information-guided design strategies and tools could unlock the creativity of a wide spectrum of scientists and engineers by decoupling expertise from implementation.

摘要

工程化生物合成途径来合成天然产物是一项极具挑战性的工作，有望为我们提供新的治疗方法和工具来操控生物学。信息指导的设计策略和工具可以通过将专业知识与实施过程分离，为广泛的科学家和工程师释放创造力。