Department of Chemistry, Tufts University, Medford, Massachusetts, USA.
Nat Chem Biol. 2010 Dec;6(12):868-70. doi: 10.1038/nchembio.469.
Chemical biology is now able to discover molecules that manipulate virtually any biological target or process. It remains a grand challenge to leverage these molecules into useful probes that can be used to address unsolved problems in biology.
化学生物学现在能够发现可以操纵几乎任何生物靶标或过程的分子。利用这些分子开发成有用的探针,以解决生物学中尚未解决的问题,仍然是一个巨大的挑战。