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大挑战述评:合成免疫学工程人类免疫

Grand challenge commentary: Synthetic immunology to engineer human immunity.

机构信息

Department of Chemistry, Yale University, New Haven, Connecticut, USA.

出版信息

Nat Chem Biol. 2010 Dec;6(12):871-2. doi: 10.1038/nchembio.477.

DOI:10.1038/nchembio.477
PMID:21079593
Abstract

Rationally designing new strategies to control the human immune response stands as a key challenge for the scientific community. Chemical biologists have the opportunity to address specific issues in this area that have important implications for both basic science and clinical medicine.

摘要

理性设计新策略来控制人体免疫反应是科学界面临的一项关键挑战。化学生物学家有机会解决这一领域的具体问题,这些问题对基础科学和临床医学都有重要意义。

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A biosynthetic strategy for re-engineering the Staphylococcus aureus cell wall with non-native small molecules.一种利用非天然小分子重新设计金黄色葡萄球菌细胞壁的生物合成策略。
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