Department of Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island, USA.
Nat Immunol. 2010 Dec;11(12):1080-2. doi: 10.1038/ni1210-1080.
Natural killer cells have emerged as key components of innate immunity with critical antimicrobial functions. New work showing that they can also be accessed by vaccination to deliver antigen-specific memory responses and protect against subsequent viral infections challenges the traditional distinctions made between innate and adaptive immunity.
自然杀伤细胞已成为先天免疫的关键组成部分,具有重要的抗微生物功能。新的研究表明,它们也可以通过疫苗接种来获得,从而提供抗原特异性记忆反应,并防止随后的病毒感染,这挑战了先天免疫和适应性免疫之间的传统区别。