Department of Otolaryngology-Head and Neck Surgery, The Mater Misericordiae Hospital, 70 Eccles Street, Dublin, Ireland.
Eur Arch Otorhinolaryngol. 2011 Apr;268(4):555-60. doi: 10.1007/s00405-010-1423-8. Epub 2010 Nov 16.
Our objective is to present a short series of four rare cases of ectopic olfactory neuroblastoma. Our methods present four case reports of ectopic olfactory neuroblastoma and a review of the literature for management and treatment of this disease. The results indicate short case series reports of ectopic olfactory neuroblastoma arising from the anterior ethmoidal sinuses, the nasopharynx, the lateral nasal wall and the floor of the nose. The discussion focuses on likely origins of ectopic olfactory neuroblastoma, its clinical features and management. We conclude that ectopic olfactory neuroblastoma is a rare disease. Treatment principles are the same for non-ectopic disease and guided by extension into adjacent structures such as the orbit or anterior cranial fossa and usually involves surgery with or without adjuvant radiotherapy.
我们的目的是呈现四例罕见的异位嗅神经母细胞瘤的短系列病例。我们的方法呈现了四例异位嗅神经母细胞瘤的病例报告，并对该疾病的管理和治疗进行了文献复习。结果表明，异位嗅神经母细胞瘤起源于前筛窦、鼻咽部、鼻腔外侧壁和鼻底部的短病例系列报告。讨论集中在异位嗅神经母细胞瘤的可能起源、其临床特征和管理上。我们的结论是，异位嗅神经母细胞瘤是一种罕见的疾病。治疗原则与非异位疾病相同，根据向眼眶或前颅窝等邻近结构的扩展而定，通常包括手术治疗，辅以放疗。
